Triflusal: An Antiplatelet Drug with a Neuroprotective Effect?
نویسندگان
چکیده
منابع مشابه
Triflusal: an old drug in modern antiplatelet therapy. Review of its action, use, safety and effectiveness.
D espite preventive measures and improved long-term prognosis, the prevalence of cardiovascular diseases in the majority of the industrialised countries is still high. The epidemic of obesity, diabetes, and metabolic syndrome, and the increasing age of the population are the major contributors to this epidemiological fact, whose socio-economic consequences are of profound importance. Over 200,0...
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Purpose: To assess the influence of smoking cigarettes on the pharmacokinetics of the antiplatelet drug, clopidogrel. Methods: Thirty four male patients, mean age and weight of 59.3 years and 81.1 kg, respectively, who underwent percutaneous coronary intervention (PCI), took part in the study. Each subject received an oral loading dose of 600 mg clopidogrel eight tablets, each 75 mg). Clopidogr...
متن کاملDecrease of proinflammatory molecules correlates with neuroprotective effect of the fluorinated salicylate triflusal after postnatal excitotoxic damage.
BACKGROUND AND PURPOSE The fluorinated salicylate triflusal has been shown to have a neuroprotective effect after an excitotoxic lesion to the postnatal brain. In this regard, the aim of this study was to elucidate whether neuroprotection was associated with changes in the expression of proinflammatory molecules such as interleukin-1beta (IL-1beta), tumor necrosis factor-alpha (TNF-alpha), indu...
متن کاملAtypical photosensitivity associated with triflusal.
An 87-year-old man was referred to our photobiology unit in August 2015 for the diagnosis and treatment of eczematous lesions involving the sun-exposed areas (face, dorsal aspects of hands, and feet) that he had suffered from for >5 years. He had suffered from hypertension, and had experienced a cerebrovascular accident 10 years previously. Since then, triflusal (300mg twice daily) has been pre...
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Ticagrelor (Brilinta) for acute coronary syndrome.
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ژورنال
عنوان ژورنال: Cardiovascular Drug Reviews
سال: 2006
ISSN: 0897-5957,1527-3466
DOI: 10.1111/j.1527-3466.2006.00011.x